BDBM50293694 CHEMBL560556::N-(4-(4-methyl-6-(5-methyl-1H-pyrazol-3-ylamino)pyrimidin-2-ylthio)phenyl)propionamide

SMILES CCC(=O)Nc1ccc(Sc2nc(C)cc(Nc3cc(C)n[nH]3)n2)cc1

InChI Key InChIKey=NHMACPMXYHTADL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293694   

TargetAurora kinase A(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293694(CHEMBL560556 | N-(4-(4-methyl-6-(5-methyl-1H-pyraz...)
Affinity DataKi:  5.10nMAssay Description:Inhibition of Aurora-A by coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293694(CHEMBL560556 | N-(4-(4-methyl-6-(5-methyl-1H-pyraz...)
Affinity DataKi:  153nMAssay Description:Inhibition of Aurora-BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed