BDBM50293698 CHEMBL563682::N-(4-(4-(azetidin-1-yl)-6-(5-methyl-1H-pyrazol-3-ylamino)pyrimidin-2-ylthio)phenyl)propionamide

SMILES CCC(=O)Nc1ccc(Sc2nc(Nc3cc(C)n[nH]3)cc(n2)N2CCC2)cc1

InChI Key InChIKey=LEWVUPUKJSFGLR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293698   

TargetAurora kinase A(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293698(CHEMBL563682 | N-(4-(4-(azetidin-1-yl)-6-(5-methyl...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of Aurora-A by coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293698(CHEMBL563682 | N-(4-(4-(azetidin-1-yl)-6-(5-methyl...)
Affinity DataKi:  23nMAssay Description:Inhibition of Aurora-BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed