BDBM50293716 CHEMBL562232::N-(3-chloro-4-methoxyphenyl)picolinamide::cid_2442621

SMILES COc1ccc(NC(=O)c2ccccn2)cc1Cl

InChI Key InChIKey=PVSOSEFQZZHTGM-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293716   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt Screening Center For Gpcrs, Ion Channels And Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293716(CHEMBL562232 | N-(3-chloro-4-methoxyphenyl)picolin...)
Affinity DataEC50:  1.05E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50293716(CHEMBL562232 | N-(3-chloro-4-methoxyphenyl)picolin...)
Affinity DataEC50:  740nMAssay Description:Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt Screening Center For Gpcrs, Ion Channels And Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293716(CHEMBL562232 | N-(3-chloro-4-methoxyphenyl)picolin...)
Affinity DataEC50:  1.10E+3nMAssay Description:Activity at human mGluR4 receptor expressed in CHO cells assessed as effect on calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4 [Q124R](Rattus norvegicus)
Vanderbilt Screening Center For Gpcrs, Ion Channels And Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293716(CHEMBL562232 | N-(3-chloro-4-methoxyphenyl)picolin...)
Affinity DataEC50:  738nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay