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BDBM50294387 CHEMBL558685::N-(3-(Benzo[d]thiazol-2-yl)thiophen-2-yl)-3-chloro-4-methylbenzenesulfonamide

SMILES: Cc1ccc(cc1Cl)S(=O)(=O)Nc1sccc1-c1nc2ccccc2s1

InChI Key: InChIKey=KQENPSNVARVVKF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294387   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Antrax lethal toxin


(Bacillus anthracis)
BDBM50294387
PNG
(CHEMBL558685 | N-(3-(Benzo[d]thiazol-2-yl)thiophen...)
Show SMILES Cc1ccc(cc1Cl)S(=O)(=O)Nc1sccc1-c1nc2ccccc2s1
Show InChI InChI=1S/C18H13ClN2O2S3/c1-11-6-7-12(10-14(11)19)26(22,23)21-18-13(8-9-24-18)17-20-15-4-2-3-5-16(15)25-17/h2-10,21H,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.60E+3n/an/an/an/an/an/a



Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis lethal factor assessed as cleavage of MAPKK by fluorescence peptide cleavage assay


Bioorg Med Chem 17: 3352-68 (2009)


Article DOI: 10.1016/j.bmc.2009.03.040
BindingDB Entry DOI: 10.7270/Q2D50N0X
More data for this
Ligand-Target Pair