BDBM50294553 1-Methoxy-3-methyl-5-phenethyl-5,6,7,12-tetrahydro-4,5,12-triaza-dibenzo[a,e]azulene::CHEMBL563257

SMILES COc1cc(C)nc2N(CCc3ccccc3)CCc3c([nH]c4ccccc34)-c12

InChI Key InChIKey=BRKIQLMANMDSLF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50294553   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294553(1-Methoxy-3-methyl-5-phenethyl-5,6,7,12-tetrahydro...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of 6xHis-tagged human NPM-ALK expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294553(1-Methoxy-3-methyl-5-phenethyl-5,6,7,12-tetrahydro...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human recombinant IRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294553(1-Methoxy-3-methyl-5-phenethyl-5,6,7,12-tetrahydro...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of recombinant METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294553(1-Methoxy-3-methyl-5-phenethyl-5,6,7,12-tetrahydro...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of recombinant JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294553(1-Methoxy-3-methyl-5-phenethyl-5,6,7,12-tetrahydro...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of recombinant IGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed