BDBM50294715 4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3-yl)butyl)amino)-2-chlorobenzonitrile::CHEMBL562509

SMILES CCCC(N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1)c1nncn1C

InChI Key InChIKey=SPSACPMSSOTZPR-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50294715   

TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294715(4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294715(4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...)
Affinity DataIC50:  110nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294715(4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...)
Affinity DataEC50:  0.0500nMAssay Description:Agonist activity at progesterone receptor in human T47D cells by alkaline phosphatase release based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed