BDBM50246289 3-methyl-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)quinazolin-4(3H)-one::CHEMBL488248::CHEMBL557214

SMILES: Cn1c(nc2ccccc2c1=O)-c1ccc(OCCCN2CCCC2)cc1

InChI Key: InChIKey=PRPSMPHMELIHFQ-UHFFFAOYSA-N

Data: 4 KI  7 IC50  2 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50246289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Human)	BDBM50246289 (CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50246289 (CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50246289 (CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Mouse)	BDBM50246289 (CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.60	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50246289 (CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H2 receptor (Human)	BDBM50246289 (CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H4 receptor (Human)	BDBM50246289 (CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Mouse)	BDBM50246289 (CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Mouse)	BDBM50246289 (CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50246289 (CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50246289 (CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		0.219	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Mouse)	BDBM50246289 (CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50246289 (CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Rat)	BDBM50246289 (CHEMBL488248 | CHEMBL557214 | 3-methyl-2-(4-(3-(py...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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