BDBM50295287 2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetic acid::CHEMBL1020::MCN-2559::TOLMETIN::Tolectin::[1-Methyl-5-(4-methyl-benzoyl)-1H-pyrrol-2-yl]-acetic acid::[1-Methyl-5-(4-methyl-benzoyl)-1H-pyrrol-2-yl]-acetic acid(tolmetin)

SMILES: Cc1ccc(cc1)C(=O)c2ccc(n2C)CC(=O)O

InChI Key: InChIKey=UPSPUYADGBWSHF-UHFFFAOYSA-N

Data: 9 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50295287   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldo-keto reductase family 1 member B1 (Human)	BDBM50295287 (2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM50295287 (2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM50295287 (2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
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Interleukin-8 (Human)	BDBM50295287 (2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM50295287 (2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...) Show SMILES Show InChI	GoogleScholar	UniChem		350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM50295287 (2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...) Show SMILES Show InChI	GoogleScholar	UniChem		820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM50295287 (2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...) Show SMILES Show InChI	GoogleScholar	UniChem		1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM50295287 (2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50295287 (2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...) Show SMILES Show InChI	GoogleScholar	UniChem		2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Lactoylglutathione lyase (Human)	BDBM50295287 (2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...) Show SMILES Show InChI	GoogleScholar	UniChem		8.78E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Lactoylglutathione lyase (Human)	BDBM50295287 (2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...) Show SMILES Show InChI	GoogleScholar	UniChem		8.78E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Albumin (Human)	BDBM50295287 (2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...) Show SMILES Show InChI	GoogleScholar	UniChem		4.16E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Lactoylglutathione lyase (Human)	BDBM50295287 (2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...) Show SMILES Show InChI	GoogleScholar	UniChem		1.01E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair