BDBM50295560 2-METHYLIMIDAZOLE::2-Methyl-1H-imidazole::CHEMBL293391::US9138393, 2-Methylimidazole::US9144538, 2-Methylimidazole

SMILES Cc1ncc[nH]1

InChI Key InChIKey=LXBGSDVWAMZHDD-UHFFFAOYSA-N

Data  3 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50295560   

TargetCytochrome P450 3A4(Homo sapiens (Human))
The Procter & Gamble

US Patent
LigandPNGBDBM50295560(2-METHYLIMIDAZOLE | 2-Methyl-1H-imidazole | CHEMBL...)
Affinity DataIC50: >1.00E+4nMAssay Description:A commercially available P450-GLO Assay kit (Promega Corporation, Madison Wis.) is used to screen various compounds for CYP3A4A inhibition activity. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Procter & Gamble

US Patent
LigandPNGBDBM50295560(2-METHYLIMIDAZOLE | 2-Methyl-1H-imidazole | CHEMBL...)
Affinity DataIC50:  1.25E+6nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Procter & Gamble

US Patent
LigandPNGBDBM50295560(2-METHYLIMIDAZOLE | 2-Methyl-1H-imidazole | CHEMBL...)
Affinity DataIC50: >1.00E+4nMAssay Description:Cytochrome P450 is a large and diverse group of enzymes that catalyze the oxidation of organic substances. Some members of the CYP family contribute ...More data for this Ligand-Target Pair
In DepthDetails US Patent