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BDBM50295824 3-(4-methoxyphenyl)-2,4-dioxo-N-(2-(piperidin-1-yl)ethyl)-1,2,3,4-tetrahydroquinazoline-7-carboxamide::CHEMBL224701::KKHT-10606

SMILES: COc1ccc(cc1)-n1c(=O)[nH]c2cc(ccc2c1=O)C(=O)NCCN1CCCCC1

InChI Key: InChIKey=DPMQWTNICFCLFP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295824   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 3A


(Homo sapiens (Human))
BDBM50295824
PNG
(3-(4-methoxyphenyl)-2,4-dioxo-N-(2-(piperidin-1-yl...)
Show SMILES COc1ccc(cc1)-n1c(=O)[nH]c2cc(ccc2c1=O)C(=O)NCCN1CCCCC1
Show InChI InChI=1S/C23H26N4O4/c1-31-18-8-6-17(7-9-18)27-22(29)19-10-5-16(15-20(19)25-23(27)30)21(28)24-11-14-26-12-3-2-4-13-26/h5-10,15H,2-4,11-14H2,1H3,(H,24,28)(H,25,30)
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Similars

Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



Konkuk University

Curated by ChEMBL


Assay Description
Antagonist activity at 5HT3A receptor expressed in Xenopus oocyte


Bioorg Med Chem 17: 4793-6 (2009)


Article DOI: 10.1016/j.bmc.2009.04.029
BindingDB Entry DOI: 10.7270/Q2668F4R
More data for this
Ligand-Target Pair