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BDBM50295916 3-(6-Fluoro-1-(3-(dimethylamino)propyl)-1H-indol-3-yl)-4-(1H-pyrrolo[3,2-b]pyridin-1-yl)-1H-pyrrole-2,5-dione::CHEMBL559241

SMILES: CN(C)CCCn1cc(C2=C(C(=O)NC2=O)n2ccc3ncccc23)c2ccc(F)cc12

InChI Key: InChIKey=XZEICVLBXWDBAH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295916   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM50295916
PNG
(3-(6-Fluoro-1-(3-(dimethylamino)propyl)-1H-indol-3...)
Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)n2ccc3ncccc23)c2ccc(F)cc12
Show InChI InChI=1S/C24H22FN5O2/c1-28(2)10-4-11-29-14-17(16-7-6-15(25)13-20(16)29)21-22(24(32)27-23(21)31)30-12-8-18-19(30)5-3-9-26-18/h3,5-9,12-14H,4,10-11H2,1-2H3,(H,27,31,32)
PDB
MMDB

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UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.24E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-GSK3beta expressed in Escherichia coli BL21 (DE3)


Bioorg Med Chem 17: 4302-12 (2009)


Article DOI: 10.1016/j.bmc.2009.05.031
BindingDB Entry DOI: 10.7270/Q2XP750M
More data for this
Ligand-Target Pair