BDBM50296003 4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid::CHEMBL550795
SMILES OC(=O)c1ccc(cc1)-c1c[nH]c2ncc(cc12)-c1ccccc1
InChI Key InChIKey=KSFDVNIKNYXUIP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50296003
Affinity DataIC50: 40nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 182nMAssay Description:Inhibition of recombinant human His-tagged AXL expressed in insect cells after 60 mins by Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiologica...More data for this Ligand-Target Pair