BDBM50296354 CHEMBL549369::N-(5-(3,5-difluorophenylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-4-(4-methylpiperazin-1-yl)benzamide

SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1[nH]nc2CCN(Cc12)S(=O)(=O)c1cc(F)cc(F)c1

InChI Key InChIKey=FYWUYAPXFLZJIW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296354   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50296354(CHEMBL549369 | N-(5-(3,5-difluorophenylsulfonyl)-4...)
Affinity DataIC50:  3.05E+3nMAssay Description:Inhibition for IGF1R-induced S6 ribosomal protein phosphorylation in growth factor-stimulated NHDFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50296354(CHEMBL549369 | N-(5-(3,5-difluorophenylsulfonyl)-4...)
Affinity DataIC50:  340nMAssay Description:Inhibition of IGF1R in growth factor-stimulated NHDFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed