BDBM50296355 CHEMBL553443::N-(2-(5-(3,5-difluorophenylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-ylcarbamoyl)-5-(4-methylpiperazin-1-yl)phenyl)-1H-pyrrole-2-carboxamide

SMILES CN1CCN(CC1)c1ccc(C(=O)Nc2[nH]nc3CCN(Cc23)S(=O)(=O)c2cc(F)cc(F)c2)c(NC(=O)c2ccc[nH]2)c1

InChI Key InChIKey=OBOJCDJVZLTBDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296355   

TargetInsulin-like growth factor 1 receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296355(N-(2-(5-(3,5-difluorophenylsulfonyl)-4,5,6,7-tetra...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human GST-tagged IGF1R by trans-phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296355(N-(2-(5-(3,5-difluorophenylsulfonyl)-4,5,6,7-tetra...)
Affinity DataIC50: 80nMAssay Description:Inhibition of IGF1R in human MCF7 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed