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BDBM50296435 2-(4-benzyl-5-(3-methylphenethyl)-4H-1,2,4-triazol-3-ylthio)acetic acid::CHEMBL550865

SMILES: Cc1cccc(CCc2nnc(SCC(O)=O)n2Cc2ccccc2)c1

InChI Key: InChIKey=MDMVPCRIAADUHD-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50296435   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296435
PNG
(2-(4-benzyl-5-(3-methylphenethyl)-4H-1,2,4-triazol...)
Show SMILES Cc1cccc(CCc2nnc(SCC(O)=O)n2Cc2ccccc2)c1
Show InChI InChI=1S/C20H21N3O2S/c1-15-6-5-9-16(12-15)10-11-18-21-22-20(26-14-19(24)25)23(18)13-17-7-3-2-4-8-17/h2-9,12H,10-11,13-14H2,1H3,(H,24,25)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
5.70E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Eur J Med Chem 44: 3266-71 (2009)


Article DOI: 10.1016/j.ejmech.2009.03.034
BindingDB Entry DOI: 10.7270/Q26110C4
More data for this
Ligand-Target Pair
Thrombin-activatable fibrinolysis (TAFI)


(Homo sapiens (Human))
BDBM50296435
PNG
(2-(4-benzyl-5-(3-methylphenethyl)-4H-1,2,4-triazol...)
Show SMILES Cc1cccc(CCc2nnc(SCC(O)=O)n2Cc2ccccc2)c1
Show InChI InChI=1S/C20H21N3O2S/c1-15-6-5-9-16(12-15)10-11-18-21-22-20(26-14-19(24)25)23(18)13-17-7-3-2-4-8-17/h2-9,12H,10-11,13-14H2,1H3,(H,24,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.96E+5n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris system


Eur J Med Chem 44: 3266-71 (2009)


Article DOI: 10.1016/j.ejmech.2009.03.034
BindingDB Entry DOI: 10.7270/Q26110C4
More data for this
Ligand-Target Pair
Carboxypeptidase A1


(Bos taurus (bovine))
BDBM50296435
PNG
(2-(4-benzyl-5-(3-methylphenethyl)-4H-1,2,4-triazol...)
Show SMILES Cc1cccc(CCc2nnc(SCC(O)=O)n2Cc2ccccc2)c1
Show InChI InChI=1S/C20H21N3O2S/c1-15-6-5-9-16(12-15)10-11-18-21-22-20(26-14-19(24)25)23(18)13-17-7-3-2-4-8-17/h2-9,12H,10-11,13-14H2,1H3,(H,24,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.17E+5n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of bovine carboxypeptidase A1


Eur J Med Chem 44: 3266-71 (2009)


Article DOI: 10.1016/j.ejmech.2009.03.034
BindingDB Entry DOI: 10.7270/Q26110C4
More data for this
Ligand-Target Pair