BDBM50296453 5-((1H-indol-3-yl)methylene)-2-(3,5-dichlorophenylamino)thiazol-4(5H)-one::CHEMBL557113

SMILES Clc1cc(Cl)cc(NC2=NC(=O)C(S2)=Cc2c[nH]c3ccccc23)c1

InChI Key InChIKey=YPGKAUICNLTEKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296453   

TargetM-phase inducer phosphatase 2(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296453(5-((1H-indol-3-yl)methylene)-2-(3,5-dichlorophenyl...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296453(5-((1H-indol-3-yl)methylene)-2-(3,5-dichlorophenyl...)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of N-terminal 6xHis-tagged human Cdc25A (336-523) catalytic domain expressed in Escherichia coli after 20 mins by fluorescent plate reader...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed