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BDBM50296576 2-(3-chloro-5-methylphenyl)-1H-indole-5-carboximidamide::CHEMBL563745

SMILES: Cc1cc(Cl)cc(c1)-c1cc2cc(ccc2[nH]1)C(N)=N

InChI Key: InChIKey=BGMVUCABLHEDJF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296576   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Amiloride-sensitive cation channel 3


(Homo sapiens (Human))
BDBM50296576
PNG
(2-(3-chloro-5-methylphenyl)-1H-indole-5-carboximid...)
Show SMILES Cc1cc(Cl)cc(c1)-c1cc2cc(ccc2[nH]1)C(N)=N
Show InChI InChI=1S/C16H14ClN3/c1-9-4-11(7-13(17)5-9)15-8-12-6-10(16(18)19)2-3-14(12)20-15/h2-8,20H,1H3,(H3,18,19)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 5.10E+4n/an/an/an/an/an/a



Merck

Curated by ChEMBL


Assay Description
Inhibition of ASIC3 by patch-clamp electrophysiology assay


Bioorg Med Chem Lett 19: 4059-63 (2009)


Article DOI: 10.1016/j.bmcl.2009.06.021
BindingDB Entry DOI: 10.7270/Q2RR1Z8K
More data for this
Ligand-Target Pair