BDBM50296667 3-(2-chloro-8-methylquinolin-3-yl)-1-phenylprop-2-en-1-one::CHEMBL561189
SMILES Cc1cccc2cc(\C=C\C(=O)c3ccccc3)c(Cl)nc12
InChI Key InChIKey=ATJXEFUUCNCHAP-ZHACJKMWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50296667
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merz Pharmaceuticals
Curated by ChEMBL
Merz Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]MPEP from mGluR5 in rat cortical membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:Allosteric antagonist activity at mGluR1 in Sprague-Dawley rat cerebellar granule cells assessed as accumulation of [3H]inositol phosphate by liquid ...More data for this Ligand-Target Pair