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BDBM50296905 CHEMBL562077::N-((1-(4-chlorophenyl)-5-(2,4-dichlorophenyl)-2-methyl-1H-pyrrol-3-yl)methyl)cyclopentanamine

SMILES: Cc1c(CNC2CCCC2)cc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1

InChI Key: InChIKey=OLISMADMBSPGGN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296905   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))
BDBM50296905
PNG
(CHEMBL562077 | N-((1-(4-chlorophenyl)-5-(2,4-dichl...)
Show SMILES Cc1c(CNC2CCCC2)cc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H23Cl3N2/c1-15-16(14-27-19-4-2-3-5-19)12-23(21-11-8-18(25)13-22(21)26)28(15)20-9-6-17(24)7-10-20/h6-13,19,27H,2-5,14H2,1H3
PDB

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PC cid
PC sid
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Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Banyu Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cells


Bioorg Med Chem Lett 19: 4611-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.06.095
BindingDB Entry DOI: 10.7270/Q2TM7B4V
More data for this
Ligand-Target Pair