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BDBM50297275 3-[2-Indol-1-yl-ethyl]-1H-indole::CHEMBL552214

SMILES: C(Cn1ccc2ccccc12)c1c[nH]c2ccccc12

InChI Key: InChIKey=QTHJXQCOLGYAGN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297275   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclin-dependent kinase 2


(Homo sapiens (Human))
BDBM50297275
PNG
(3-[2-Indol-1-yl-ethyl]-1H-indole | CHEMBL552214)
Show SMILES C(Cn1ccc2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C18H16N2/c1-4-8-18-14(5-1)9-11-20(18)12-10-15-13-19-17-7-3-2-6-16(15)17/h1-9,11,13,19H,10,12H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



University of Leicester

Curated by ChEMBL


Assay Description
Inhibition of human CDK2/ Cyclin A catalytic subunit expressed in Sf9 insect cells assessed as histone H1 phosphorylation-associated depletion in ATP...


Bioorg Med Chem 17: 6073-84 (2009)


Article DOI: 10.1016/j.bmc.2009.06.070
BindingDB Entry DOI: 10.7270/Q27P8ZDP
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 4


(Homo sapiens (Human))
BDBM50297275
PNG
(3-[2-Indol-1-yl-ethyl]-1H-indole | CHEMBL552214)
Show SMILES C(Cn1ccc2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C18H16N2/c1-4-8-18-14(5-1)9-11-20(18)12-10-15-13-19-17-7-3-2-6-16(15)17/h1-9,11,13,19H,10,12H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



University of Leicester

Curated by ChEMBL


Assay Description
Inhibition of human CDK4/ Cyclin D1 catalytic subunit expressed in Sf9 insect cells assessed as GST-RB152 fusion protein phosphorylation-associated d...


Bioorg Med Chem 17: 6073-84 (2009)


Article DOI: 10.1016/j.bmc.2009.06.070
BindingDB Entry DOI: 10.7270/Q27P8ZDP
More data for this
Ligand-Target Pair