BDBM50297319 CHEMBL550261::Piperidin-1-yl(4-(spiro[chromene-2,4'-piperidine]-4-yl)phenyl)methanone

SMILES O=C(N1CCCCC1)c1ccc(cc1)C1=CC2(CCNCC2)Oc2ccccc12

InChI Key InChIKey=NEEISBJRSKJUGD-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50297319   

TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50297319(CHEMBL550261 | Piperidin-1-yl(4-(spiro[chromene-2,...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50297319(CHEMBL550261 | Piperidin-1-yl(4-(spiro[chromene-2,...)
Affinity DataIC50:  3.03E+3nMAssay Description:Inhibition of human ERG channel expressed in HEK293 cells by voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50297319(CHEMBL550261 | Piperidin-1-yl(4-(spiro[chromene-2,...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50297319(CHEMBL550261 | Piperidin-1-yl(4-(spiro[chromene-2,...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed