BDBM50297322 CHEMBL551536::N-Benzyl-N-methyl-4-(spiro[chromene-2,4'-piperidine]-4-yl)-benzamide
SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)C1=CC2(CCNCC2)Oc2ccccc12
InChI Key InChIKey=NGDWGFGKTHXWNQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50297322
Affinity DataKi: 18nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence-based assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Adolor
Curated by ChEMBL
Adolor
Curated by ChEMBL
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of human ERG channel expressed in HEK293 cells by voltage clamp assayMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair