BDBM50001709 4-cyclopropylmethyl-(13R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-triene-10,14,17-triol::CHEMBL140278::CHEMBL558140::Naltrexone-6-beta-ol

SMILES: O[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45

InChI Key: InChIKey=JLVNEHKORQFVQJ-UHFFFAOYSA-N

Data: 6 KI  11 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50001709   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Guinea pig)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Guinea pig)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Guinea pig)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor (Human)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Guinea pig)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor (Human)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Guinea pig)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Guinea pig)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50001709 (CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		213	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair