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BDBM50297725 (4-methylpiperidin-1-yl)(6-(2-(1-methylpyrrolidin-2-yl)ethoxy)naphthalen-2-yl)methanone::CHEMBL563869

SMILES: CC1CCN(CC1)C(=O)c1ccc2cc(OCCC3CCCN3C)ccc2c1

InChI Key: InChIKey=BGOMQIUNKLIQLP-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297725   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50297725
PNG
((4-methylpiperidin-1-yl)(6-(2-(1-methylpyrrolidin-...)
Show SMILES CC1CCN(CC1)C(=O)c1ccc2cc(OCCC3CCCN3C)ccc2c1
Show InChI InChI=1/C24H32N2O2/c1-18-9-13-26(14-10-18)24(27)21-6-5-20-17-23(8-7-19(20)16-21)28-15-11-22-4-3-12-25(22)2/h5-8,16-18,22H,3-4,9-15H2,1-2H3
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PC cid
PC sid
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Similars

Article
PubMed
571n/an/an/an/an/an/an/an/a



Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Inhibition of human histamine H3 expressed in CHO cells by saturation binding experiment


Bioorg Med Chem Lett 19: 4495-500 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.100
BindingDB Entry DOI: 10.7270/Q2MS3STJ
More data for this
Ligand-Target Pair