BDBM50298132 (4S)4-[({4-[4-(Methoxymethyl)piperidin-1-yl]-6-phenylpyridin-2-yl}carbonyl)amino]-5-oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}pentanoic Acid::(S)-4-(4-(4-(methoxymethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid::CHEMBL539733

SMILES CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(cc(n1)-c1ccccc1)N1CCC(COC)CC1

InChI Key InChIKey=GXVBAKBDKMEJNJ-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50298132   

TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50298132((4S)4-[({4-[4-(Methoxymethyl)piperidin-1-yl]-6-phe...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity to P2Y12 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50298132((4S)4-[({4-[4-(Methoxymethyl)piperidin-1-yl]-6-phe...)
Affinity DataKi:  15nMAssay Description:Inhibition of human P2Y12 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50298132((4S)4-[({4-[4-(Methoxymethyl)piperidin-1-yl]-6-phe...)
Affinity DataKi:  15nMAssay Description:Displacement of [33P]ADP from human recombinant P2Y12 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50298132((4S)4-[({4-[4-(Methoxymethyl)piperidin-1-yl]-6-phe...)
Affinity DataKi:  15nMAssay Description:Binding affinity to human recombinant P2Y12 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50298132((4S)4-[({4-[4-(Methoxymethyl)piperidin-1-yl]-6-phe...)
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at human P2Y12 receptor assessed as inhibition of ADP-induced platelet-rich plasma aggregation by chronolog PRP aggregometry assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50298132((4S)4-[({4-[4-(Methoxymethyl)piperidin-1-yl]-6-phe...)
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at human P2Y12 receptor assessed as inhibition of ADP-induced platelet-rich plasma aggregation by turbidimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed