BDBM50298220 2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine::2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-4-yl)-6-methylpyridine::CHEMBL1824446::CHEMBL226838::SB-505124::US11759530, Compound Table1.2

SMILES: Cc1cccc(n1)c2c([nH]c(n2)C(C)(C)C)c3ccc4c(c3)OCO4

InChI Key: InChIKey=WGZOTBUYUFBEPZ-UHFFFAOYSA-N

Data: 25 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50298220   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	594	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	668	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Activin receptor type-1B (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Mouse)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	685	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Activin receptor type-1B (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	594	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	594	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	594	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50298220 (2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair