BDBM50298533 5-[(beta-Naphthylmethyl)carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine::CHEMBL575204

SMILES Cn1cc2c(n1)nc(NC(=O)Cc1ccc3ccccc3c1)n1nc(nc21)-c1ccco1

InChI Key InChIKey=URTMGLWEEROVNL-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50298533   

TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50298533(5-[(beta-Naphthylmethyl)carbonyl]amino-8-methyl-2-...)
Affinity DataKi:  14.5nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50298533(5-[(beta-Naphthylmethyl)carbonyl]amino-8-methyl-2-...)
Affinity DataKi:  77.5nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50298533(5-[(beta-Naphthylmethyl)carbonyl]amino-8-methyl-2-...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50298533(5-[(beta-Naphthylmethyl)carbonyl]amino-8-methyl-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced adenylyl cyclase activityChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed