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BDBM50299266 (S)-2-(5-chlorobenzo[d]thiazol-2-ylthio)propanoic acid::CHEMBL583796

SMILES: C[C@H](Sc1nc2cc(Cl)ccc2s1)C(O)=O

InChI Key: InChIKey=QTSNMZSKXHZAQF-MLHKIVSYNA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299266   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50299266
PNG
((S)-2-(5-chlorobenzo[d]thiazol-2-ylthio)propanoic ...)
Show SMILES C[C@H](Sc1nc2cc(Cl)ccc2s1)C(O)=O
Show InChI InChI=1/C10H8ClNO2S2/c1-5(9(13)14)15-10-12-7-4-6(11)2-3-8(7)16-10/h2-5H,1H3,(H,13,14)/t5-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 6.25E+4n/an/an/an/a



Universit£ degli Studi G. d'Annunzio

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assay


J Med Chem 52: 6224-32 (2009)


Article DOI: 10.1021/jm900878u
BindingDB Entry DOI: 10.7270/Q2ZP465F
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50299266
PNG
((S)-2-(5-chlorobenzo[d]thiazol-2-ylthio)propanoic ...)
Show SMILES C[C@H](Sc1nc2cc(Cl)ccc2s1)C(O)=O
Show InChI InChI=1/C10H8ClNO2S2/c1-5(9(13)14)15-10-12-7-4-6(11)2-3-8(7)16-10/h2-5H,1H3,(H,13,14)/t5-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 5.59E+4n/an/an/an/a



Universit£ degli Studi G. d'Annunzio

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assay


J Med Chem 52: 6224-32 (2009)


Article DOI: 10.1021/jm900878u
BindingDB Entry DOI: 10.7270/Q2ZP465F
More data for this
Ligand-Target Pair