BDBM50299461 (S)-7-(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-3-yloxymethyl)-2-(oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid::7-(1,1-DIOXO-1H-BENZO[D]ISOTHIAZOL-3-YLOXYMETHYL)-2-(OXALYL-AMINO)-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRAN-3-CARBOXYLIC ACID::CHEMBL577144

SMILES OC(=O)C(=O)Nc1sc2[C@H](COC3=NS(=O)(=O)c4ccccc34)OCCc2c1C(O)=O

InChI Key InChIKey=MDYIGSPVMWSFEZ-JTQLQIEISA-N

Data  8 KI

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50299461   

TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Miami

Curated by ChEMBL
LigandPNGBDBM50299461((S)-7-(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-...)
Affinity DataKi:  600nMAssay Description:Inhibition of PTPN2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Miami

Curated by ChEMBL
LigandPNGBDBM50299461((S)-7-(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of PTPN1More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
University Of Miami

Curated by ChEMBL
LigandPNGBDBM50299461((S)-7-(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of PTPRBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
University Of Miami

Curated by ChEMBL
LigandPNGBDBM50299461((S)-7-(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-...)
Affinity DataKi:  1.76E+5nMAssay Description:Inhibition of PTPRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
University Of Miami

Curated by ChEMBL
LigandPNGBDBM50299461((S)-7-(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-...)
Affinity DataKi:  2.89E+5nMAssay Description:Inhibition of PTPN6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
University Of Miami

Curated by ChEMBL
LigandPNGBDBM50299461((S)-7-(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-...)
Affinity DataKi:  4.89E+5nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
University Of Miami

Curated by ChEMBL
LigandPNGBDBM50299461((S)-7-(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-...)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of PTPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase epsilon(Homo sapiens (Human))
University Of Miami

Curated by ChEMBL
LigandPNGBDBM50299461((S)-7-(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-...)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of PTPREMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed