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BDBM50299588 1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-N-o-tolylpiperidine-4-carboxamide::CHEMBL578599

SMILES: Cc1c[nH]c2ncnc(N3CCC(CC3)C(=O)Nc3ccccc3C)c12

InChI Key: InChIKey=RFPNUIOUJIEGLY-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299588   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
LIM domain kinase 2


(Homo sapiens (Human))
BDBM50299588
PNG
(1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-N-o-t...)
Show SMILES Cc1c[nH]c2ncnc(N3CCC(CC3)C(=O)Nc3ccccc3C)c12
Show InChI InChI=1S/C20H23N5O/c1-13-5-3-4-6-16(13)24-20(26)15-7-9-25(10-8-15)19-17-14(2)11-21-18(17)22-12-23-19/h3-6,11-12,15H,7-10H2,1-2H3,(H,24,26)(H,21,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.15E+4n/an/an/an/an/an/a



Princ

Curated by ChEMBL


Assay Description
Inhibition of human recombinant LIMK2 expressed in baculovirus-Sf9 system by scintillation counting


J Med Chem 52: 6515-8 (2009)


Article DOI: 10.1021/jm901226j
BindingDB Entry DOI: 10.7270/Q2HH6K4J
More data for this
Ligand-Target Pair