BDBM50299703 2-(4-Fluorophenyl)ethynyl-N6-methyl-5'-N-methylcarboxamidoadenosine::CHEMBL573269

SMILES CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC)nc(nc12)C#Cc1ccc(F)cc1

InChI Key InChIKey=ANVULPCYYRRANV-KSVNGYGVSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50299703   

TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50299703(2-(4-Fluorophenyl)ethynyl-N6-methyl-5'-N-methylcar...)
Affinity DataKi:  0.427nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50299703(2-(4-Fluorophenyl)ethynyl-N6-methyl-5'-N-methylcar...)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50299703(2-(4-Fluorophenyl)ethynyl-N6-methyl-5'-N-methylcar...)
Affinity DataKi:  5.31E+3nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50299703(2-(4-Fluorophenyl)ethynyl-N6-methyl-5'-N-methylcar...)
Affinity DataKi:  1.27E+4nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50299703(2-(4-Fluorophenyl)ethynyl-N6-methyl-5'-N-methylcar...)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed