BDBM50300032 6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morpholinoquinazolin-4-amine::CHEMBL571717

SMILES: CN1CCC(CC1)Nc2c3cc(c(cc3nc(n2)N4CCOCC4)OC)OC

InChI Key: InChIKey=MEVMMQQJOXBSAX-UHFFFAOYSA-N

Data: 6 IC50  2 Kd

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50300032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase EHMT1 (Human)	BDBM50300032 (6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Human)	BDBM50300032 (6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	445	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Human)	BDBM50300032 (6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Human)	BDBM50300032 (6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Human)	BDBM50300032 (6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Human)	BDBM50300032 (6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Human)	BDBM50300032 (6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Human)	BDBM50300032 (6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair