BDBM50300100 CHEMBL576952::trans-6-(1-benzyl-4-methylpyrrolidin-3-yl)-1-isobutyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

SMILES CC(C)Cn1ncc2c1nc([nH]c2=O)[C@@H]1CN(Cc2ccccc2)C[C@H]1C

InChI Key InChIKey=VWYPSWDBTYIGDI-CRAIPNDOSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50300100   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50300100(CHEMBL576952 | trans-6-(1-benzyl-4-methylpyrrolidi...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50300100(CHEMBL576952 | trans-6-(1-benzyl-4-methylpyrrolidi...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant PDE1C expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50300100(CHEMBL576952 | trans-6-(1-benzyl-4-methylpyrrolidi...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant PDE1C expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50300100(CHEMBL576952 | trans-6-(1-benzyl-4-methylpyrrolidi...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed