BDBM50300143 (R)-5-Chloro-3-[6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino]-1-(2-methoxy-1-methylethyl)pyrazin-2(1H)-one::CHEMBL572588

SMILES COC[C@@H](C)n1cc(Cl)nc(Nc2cc(C)c(OC(F)F)nc2C)c1=O

InChI Key InChIKey=DZTDHMGXIRVSAW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300143   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50300143((R)-5-Chloro-3-[6-(difluoromethoxy)-2,5-dimethylpy...)
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I]Tyr-o-CRF from CRF1 receptor in rat frontal cortex homogenate by binding titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed