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BDBM50300155 (1S,4R)-9-amino-4-tert-butyl-1-methyl-1,2,3,4-tetrahydroacridine::CHEMBL574794

SMILES: C[C@H]1CC[C@@H](c2nc3ccccc3c(N)c12)C(C)(C)C

InChI Key: InChIKey=FCIKKNKPLCUPCP-BJBPJPDTNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300155   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50300155
PNG
((1S,4R)-9-amino-4-tert-butyl-1-methyl-1,2,3,4-tetr...)
Show SMILES C[C@H]1CC[C@@H](c2nc3ccccc3c(N)c12)C(C)(C)C
Show InChI InChI=1/C18H24N2/c1-11-9-10-13(18(2,3)4)17-15(11)16(19)12-7-5-6-8-14(12)20-17/h5-8,11,13H,9-10H2,1-4H3,(H2,19,20)/t11-,13-/s2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.35E+3n/an/an/an/an/an/a



Universidade Federal do Rio Grande do Sul

Curated by ChEMBL


Assay Description
Inhibition of AChE from rat cortex by Ellman assay


Eur J Med Chem 45: 526-35 (2010)


Article DOI: 10.1016/j.ejmech.2009.10.039
BindingDB Entry DOI: 10.7270/Q27W6C85
More data for this
Ligand-Target Pair