BDBM50300228 (2E,5R)-5-(2-cyclohexylethyl)-5-(cyclohexylmethyl)-2-imino-3-methylimidazolidin-4-one::(R)-3-Methyl-5-cyclohexylethyl-5-cyclohexylmethyl-2-iminohydantoin::CHEMBL583178

SMILES CN1C(N)=N[C@](CCC2CCCCC2)(CC2CCCCC2)C1=O

InChI Key InChIKey=SVQNYPQKWMFQJJ-LJQANCHMSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300228   

TargetCathepsin D(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50300228((2E,5R)-5-(2-cyclohexylethyl)-5-(cyclohexylmethyl)...)
Affinity DataKi:  740nMAssay Description:Inhibition of human cathepsin D preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50300228((2E,5R)-5-(2-cyclohexylethyl)-5-(cyclohexylmethyl)...)
Affinity DataIC50:  605nMAssay Description:Inhibition of BACE1 mediated human Swedish amyloid precursor protein peptide hydrolysis by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50300228((2E,5R)-5-(2-cyclohexylethyl)-5-(cyclohexylmethyl)...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of BACE1 mediated hydrolysis of human amyloid precursor protein with Swedish and London mutation in HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed