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BDBM50300229 1-methyl-4,4-diphenyl-4,5-dihydro-1H-imidazol-2-amine::2-Imino-3-methyl-5,5-diphenyl-imidazolidin-4-one::2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-one::5,5-Diphenyl-2-iminohydantoin::CHEMBL291784
SMILES: CN1C(N)=NC(C1=O)(c1ccccc1)c1ccccc1
InChI Key: InChIKey=RNWLAFWLSSMCLN-UHFFFAOYSA-N
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Amyloid-beta precursor protein (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | n/a | n/a | 4.17E+3 | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase 1 (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | 3.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase 2 (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin D (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase 1 (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin D (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase 1 (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | 3.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase 1 (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase 2 (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase 1 (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | 3.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase 1 (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Renin (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase 2 (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase 1 (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | 3.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase 1 (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase 1 (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase 1 (Human) | BDBM50300229![]() (2-amino-1-methyl-4,4-diphenyl-1H-imidazol-5(4H)-on...) | GoogleScholar | UniChem | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||