BDBM50300905 CHEMBL578192::N-{(R)-1-[3-(4-Cyano-phenyl)-8-cyclopropyl-imidazo[1,2-a]pyrazin-2-yl]-ethyl}-N-(1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-ylmethyl)-2-(3-fluoro-4-trifluoromethyl-phenyl)-acetamide
SMILES C[C@@H](N(CC1CCS(=O)(=O)CC1)C(=O)Cc1ccc(c(F)c1)C(F)(F)F)c1nc2c(nccn2c1-c1ccc(cc1)C#N)C1CC1
InChI Key InChIKey=NQDZXGBUJMRXDE-HXUWFJFHSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50300905
Affinity DataIC50: 7.30nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMC in presence of human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 18.9nMAssay Description:Antagonistic activity to CXCR3 receptor expressed in PBMC assessed as inhibition of ITAC-mediated cell migration in presence of 100% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of ITAC from CXCR3 receptor in mouse whole blood assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Displacement of ITAC from CXCR3 receptor in human whole blood assayMore data for this Ligand-Target Pair