BDBM50300914 (R)-N-(1-(3-(4-cyanophenyl)-7-methylimidazo[1,2-a]pyrimidin-2-yl)ethyl)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trifluoromethyl)phenyl)acetamide::CHEMBL577108

SMILES CCS(=O)(=O)CCN([C@H](C)c1nc2nc(C)ccn2c1-c1ccc(cc1)C#N)C(=O)Cc1ccc(F)c(c1)C(F)(F)F

InChI Key InChIKey=LVDVKWDYPBXITC-LJQANCHMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300914   

TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50300914((R)-N-(1-(3-(4-cyanophenyl)-7-methylimidazo[1,2-a]...)
Affinity DataIC50:  100nMAssay Description:Antagonistic activity to CXCR3 receptor expressed in PBMC assessed as inhibition of ITAC-mediated cell migration in presence of 100% human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50300914((R)-N-(1-(3-(4-cyanophenyl)-7-methylimidazo[1,2-a]...)
Affinity DataIC50:  22nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMC in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50300914((R)-N-(1-(3-(4-cyanophenyl)-7-methylimidazo[1,2-a]...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed