BDBM50301113 (3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phenylpiperazine-1-carbonyl)piperidin-3-yl pyrrolidine-1-carboxylate::CHEMBL585299

SMILES CN1C[C@H](C[C@@H]([C@H]1C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO)OC(=O)N1CCCC1

InChI Key InChIKey=YYMXPNNILUETLE-UFYCRDLUSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50301113   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50301113((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50:  471nMAssay Description:Inhibition of MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50301113((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50:  18nMAssay Description:Inhibition of ADAM-10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50301113((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50:  11.5nMAssay Description:Inhibition of HER-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50301113((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50301113((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MMP-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50301113((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed