BDBM50301364 CHEMBL570380::N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyridin-2-yl)-2-oxo-1-phenyl-5-(thiophen-2-yl)-1,2-dihydropyridine-3-carboxamide
SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4cc(cn(-c5ccccc5)c4=O)-c4cccs4)nc3)c2cc1OC
InChI Key InChIKey=WZTFASVDMINVIL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50301364
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of human PyK2 Y402 autophosphorylation expressed in 293T cells by immunofluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in calcium levelMore data for this Ligand-Target Pair
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in alkaline phosphatase levelMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in osteocalcin levelMore data for this Ligand-Target Pair