BDBM50301520 4-fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)thiazol-2-yl)-N-methylbenzamide::CHEMBL566581

SMILES: CC(C)Nc1cc(ncn1)-c1csc(n1)N(C)C(=O)c1ccc(F)cc1

InChI Key: InChIKey=WIVGIKIKQHUFOD-UHFFFAOYSA-N

Data: 1 KI  7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50301520   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Human)	BDBM50301520 (4-fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
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Metabotropic glutamate receptor 1 (Human)	BDBM50301520 (4-fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Metabotropic glutamate receptor 2 (Human)	BDBM50301520 (4-fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Metabotropic glutamate receptor 8 (Human)	BDBM50301520 (4-fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Metabotropic glutamate receptor 5 (Human)	BDBM50301520 (4-fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Rat)	BDBM50301520 (4-fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50301520 (4-fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Rat)	BDBM50301520 (4-fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair