BDBM50301756 CHEMBL568235::isopropyl 2-cyano-6-(cyclohexanecarbonyl)-4,4-dimethyl-1,4,5,6-tetrahydropyrrolo[3,2-d]azepine-8-carboxylate

SMILES CC(C)OC(=O)C1=CN(CC(C)(C)c2cc([nH]c12)C#N)C(=O)C1CCCCC1

InChI Key InChIKey=XXFNZXMNEZHOIU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301756   

TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301756(CHEMBL568235 | isopropyl 2-cyano-6-(cyclohexanecar...)
Affinity DataEC50:  6.5nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed