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BDBM50301820 2-methyl-5-(5-methyl-1-(pyridin-3-yl)-1H-1,2,3-triazol-4-yl)benzo[d]thiazole::CHEMBL576231

SMILES: Cc1nc2cc(ccc2s1)-c1nnn(c1C)-c1cccnc1

InChI Key: InChIKey=TUMXYGIWQHAHFZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301820   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50301820
PNG
(2-methyl-5-(5-methyl-1-(pyridin-3-yl)-1H-1,2,3-tri...)
Show SMILES Cc1nc2cc(ccc2s1)-c1nnn(c1C)-c1cccnc1
Show InChI InChI=1S/C16H13N5S/c1-10-16(19-20-21(10)13-4-3-7-17-9-13)12-5-6-15-14(8-12)18-11(2)22-15/h3-9H,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human mGluR1 receptor expressed in CHO cell membranes assessed as inhibition of L-glutamate-induced calcium mobilization by FL...


Bioorg Med Chem Lett 19: 5310-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.145
BindingDB Entry DOI: 10.7270/Q26H4HGN
More data for this
Ligand-Target Pair