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BDBM50302184 3-amino-4-methyl-6-(piperazin-1-yl)thieno[2,3-b]pyridine-2-carboxamide::CHEMBL569813

SMILES: Cc1cc(nc2sc(C(N)=O)c(N)c12)N1CCNCC1

InChI Key: InChIKey=DDLJAULLOOCAIF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302184   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inhibitor of nuclear factor kappa-B kinase subunit beta


(Homo sapiens (Human))
BDBM50302184
PNG
(3-amino-4-methyl-6-(piperazin-1-yl)thieno[2,3-b]py...)
Show SMILES Cc1cc(nc2sc(C(N)=O)c(N)c12)N1CCNCC1
Show InChI InChI=1S/C13H17N5OS/c1-7-6-8(18-4-2-16-3-5-18)17-13-9(7)10(14)11(20-13)12(15)19/h6,16H,2-5,14H2,1H3,(H2,15,19)
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PC sid
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Similars

Article
PubMed
n/an/a 680n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of Flag epitope-tagged IKK-beta preincubated for 5 mins by scintillation proximity assay


Bioorg Med Chem Lett 19: 5547-51 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.054
BindingDB Entry DOI: 10.7270/Q22Z16G1
More data for this
Ligand-Target Pair