BDBM50302372 (4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin-7-yl)(morpholino)methanone::CHEMBL567292::GSK-554418A

SMILES Cn1ccc2c(Nc3cccc(Cl)c3)ncc(C(=O)N3CCOCC3)c12

InChI Key InChIKey=VARGWBUXBMFVJN-UHFFFAOYSA-N

Data  5 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50302372   

TargetCannabinoid receptor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50302372((4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c...)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human recombinant cannabinoid CB2 receptor expressed in CHOK1 cells assessed as forskolin-induced cAMP production by luciferase a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50302372((4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50302372((4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50302372((4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human recombinant cannabinoid CB2 receptor expressed in MMY23 Saccharomyces cerevisiae assessed as degradation of FDGlu to fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50302372((4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50302372((4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50302372((4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c...)
Affinity DataEC50:  6.30E+3nMAssay Description:Agonist activity at human recombinant cannabinoid CB1 receptor expressed in MMY23 Saccharomyces cerevisiae assessed as degradation of FDGlu to fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50302372((4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed