BDBM50302465 CHEMBL566048::N-(2-chloro-4-(N-methylsulfamoyl)benzyl)-6-(3,3,3-trifluoropropoxy)nicotinamide

SMILES CNS(=O)(=O)c1ccc(CNC(=O)c2ccc(OCCC(F)(F)F)nc2)c(Cl)c1

InChI Key InChIKey=FPXKSZDQIMNYEO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302465   

TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302465(CHEMBL566048 | N-(2-chloro-4-(N-methylsulfamoyl)be...)
Affinity DataIC50:  19nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302465(CHEMBL566048 | N-(2-chloro-4-(N-methylsulfamoyl)be...)
Affinity DataIC50:  31nMAssay Description:Inhibition of soluble EH in human HepG2 cells by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302465(CHEMBL566048 | N-(2-chloro-4-(N-methylsulfamoyl)be...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human soluble EHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed