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BDBM50302801 2-(3-chloro-5-(4-(ethylcarbamoyl)-2-(4-methylphenylsulfonamido)phenoxy)phenyl)acetic acid::CHEMBL570001

SMILES: CCNC(=O)c1ccc(Oc2cc(Cl)cc(CC(O)=O)c2)c(NS(=O)(=O)c2ccc(C)cc2)c1

InChI Key: InChIKey=LAHDXFOHXROSKF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302801   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50302801
PNG
(2-(3-chloro-5-(4-(ethylcarbamoyl)-2-(4-methylpheny...)
Show SMILES CCNC(=O)c1ccc(Oc2cc(Cl)cc(CC(O)=O)c2)c(NS(=O)(=O)c2ccc(C)cc2)c1
Show InChI InChI=1S/C24H23ClN2O6S/c1-3-26-24(30)17-6-9-22(33-19-11-16(12-23(28)29)10-18(25)14-19)21(13-17)27-34(31,32)20-7-4-15(2)5-8-20/h4-11,13-14,27H,3,12H2,1-2H3,(H,26,30)(H,28,29)
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Similars

Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGD2 from human CRTH2 expressed in HEK 293 cells in presence of 0.5% BSA by scintillation counting


Bioorg Med Chem Lett 19: 6419-23 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.052
BindingDB Entry DOI: 10.7270/Q25Q4X20
More data for this
Ligand-Target Pair