BDBM50302905 7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)-1,5-naphthyridin-4-amine::CHEMBL566685::US9066954, 4

SMILES: COc1cnc2c(NCc3nnc4ccc(nn34)-c3cc(C)ns3)ccnc2c1

InChI Key: InChIKey=QMWKLCXWSJTEFT-UHFFFAOYSA-N

Data: 2 KI  9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50302905   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Human)	BDBM50302905 (7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50302905 (7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50302905 (7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM50302905 (7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM50302905 (7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM50302905 (7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50302905 (7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM50302905 (7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50302905 (7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM50302905 (7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...) Show SMILES Show InChI	GoogleScholar	UniChem		3.20	-11.7	n/a	n/a	n/a	n/a	n/a	8.0	27
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50302905 (7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair