BDBM50303004 CHEMBL562810::mulberrofuran W

SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]/[#6]-c1c(-[#8])cc(-[#8])cc1-c1cc2ccc(-[#8])cc2o1

InChI Key InChIKey=YUFBSQFJPYHMTK-QUYCRGELSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50303004   

TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50303004(CHEMBL562810 | mulberrofuran W)
Affinity DataIC50:  700nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Korean Research Institute Of Biosciences And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50303004(CHEMBL562810 | mulberrofuran W)
Affinity DataIC50:  6.07E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human Hep3B cells by pGL3-HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Korean Research Institute Of Biosciences And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50303004(CHEMBL562810 | mulberrofuran W)
Affinity DataIC50:  3.62E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha protein accumulation in human Hep3B cells treated for 30 mins measured after 12 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50303004(CHEMBL562810 | mulberrofuran W)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed